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. 2012 Aug 7;109(38):15473–15478. doi: 10.1073/pnas.1208779109

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Fig. 1. — The methanogenic pathway. Eha, energy-converting hydrogenase A; Fdh, formate dehydrogenase; Fru and Frc, F₄₂₀-reducing hydrogenases; Ftr, formyl-MFR:H₄MPT formyltransferase; Fwd, formyl-MFR dehydrogenase; Hdr, heterodisulfide reductase; Hmd, H₂-dependent methylene-H₄MPT dehydrogenase; Mch, methenyl-H₄MPT cyclohydrolase; Mcr, methyl-CoM reductase; Mer, methylene-H₄MPT reductase; Mtd, F₄₂₀-dependent methylene-H₄MPT dehydrogenase; Mtr, methyl-H₄MPT-CoM methyltransferase; Vhu and Vhc, F₄₂₀-nonreducing (Hdr-associated) hydrogenases.