Figure 5.

Cell surface half-life (A) and internalization rate (B) of IL2Rβ on IARC301.5 cells treated with or without the proteasome inhibitor lactacystin. Cells were preincubated for 3 h at 37°C before and during the assays with 12.5 μM lactacystin or with control medium and the experiments were performed as described in Figure 1. The results presented in A and B are the means ± SE of at least three independent experiments.