Figure 3.

Determination of cross-linking by lectins in mucin mimetic arrays. (A) Cross-linking by lectin does not occur and the observed dissociation constant should be independent of glycolpolymer surface density. (B) Cross-linking is a contributing factor and increasing separation between neighboring mucin mimetic molecules should result in weaker binding (K_d,high and K_d,low denote apparent dissociation constants determined for a lectin in a high and a low glycopolymer surface density array, respectively).