Comparison of 2D annular area (Panel A), annular circumference (Panel B), septolateral diameter (Panel C), mitral valve transverse diameter (Panel D) and annular height (Panel E) for normal (black), ischemic (green) and myxomatous (red) annuli after being normalized to annulus size at the time of valve opening. Systolic changes in these measures were significantly different among groups by MANOVA, P=0.02. Ischemic annuli appear to have less contraction and motion compared to normal annuli. In contrast, mxyomatous annuli appear to demonstrate rapid systolic dilatation compared to normal and ischemic annuli. Dotted lines=standard error of the mean