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Overexpression of Myc-mLin-7 deletion mutants interfered with the basolateral sorting of P75t-Let23WT. These panels depict the results of an endocytosis experiment similar to that described in Figure 7A, but performed with MDCK cell lines coexpressing P75t-Let23WT with Myc-mLin-7WT, Myc-mLin-7N, or Myc-mLin-7PDZ (see Figure 3 for description of mLin-7 constructs). The panels show Z-sections at time 0 and 120 min, and the apical (Ap) and basolateral (Bl) sides are indicated.
