Table 3.
Risk of anastomotic leakage confirmed at reoperation based on univariate logistic regression analyses
| Variable | P | Odds ratio (95% CI) |
|---|---|---|
| NSAID use and drug type | <0.001 | — |
| None | — | 1 |
| Ibuprofen | 0.003 | 1.68 (1.19 to 2.38) |
| Diclofenac | <0.001 | 2.75 (1.77 to 4.28) |
| Intraoperative transfusion | <0.001 | 5.14 (3.77 to7.02) |
| Rectal v colonic resection | <0.001 | 1.87 (1.37 to 2.54) |
| Male sex | 0.001 | 1.74 (1.27 to 2.39) |
| Surgical centre* | 0.002 | — |
| 1 | — | 1 |
| 2 | 0.03 | 0.11 (0.02 to 0.82) |
| 3 | 0.05 | 0.56 (0.32 to 1.00) |
| 4 | 0.12 | 1.39 (0.92 to 2.11) |
| 5 | 0.76 | 1.08 (0.66 to 1.76) |
| 6 | 0.07 | 1.51 (0.98 to 2.35) |
| Age | 0.14 | 0.90 (0.79 to 1.03)† |
| Intraoperative blood loss | 0.17 | 1.02 (0.99 to 1.04)‡ |
| ASA score | 0.23 | — |
| I | — | 1 |
| II | 0.90 | 1.02 (0.70 to 1.51) |
| III | 0.10 | 1.75 (0.93 to 2.39) |
| Laparoscopic v open surgery | 0.24 | 0.83 (0.61 to 1.13) |
| Tumour T stage | 0.90 | — |
| 4 | — | 1 |
| 3 | 1.00 | 1.00 (0.48 to 2.09) |
| 2 | 0.79 | 0.92 (0.52 to 1.66) |
| 1 | 0.66 | 1.09 (0.73 to 1.64) |
ASA=American Society of Anesthesiologists.
*Centres numbered from 1 to 6.
†For each increment of 10 years.
‡For each increment of 100 mL.