Table 1. Association with ABCB1 gene expression of imputed loci with top-ranked BFs using 1000 Genome datasets as reference panels.
SNP | Position | A1 A2 | Infor(Impute) | MAF | Log10(BF) | P Value |
rs28373093 | 87344023 | C G | 0.654 | 0.423 | 2.011 | 4.00E-05 |
rs35901799 | 87344022 | C T | 0.658 | 0.427 | 1.977 | 4.00E-05 |
rs1002205 | 87141174 | C G | 0.893 | 0.402 | 1.886 | 8.00E-05 |
rs1029421 | 87418861 | C T | 0.888 | 0.48 | 1.853 | 1.30E-04 |
rs6966166 | 87455155 | T C | 0.919 | 0.46 | 1.773 | 1.60E-04 |
rs7779623 | 87391761 | G A | 0.925 | 0.463 | 1.767 | 1.50E-04 |
rs34800935 | 87256602 | C T | 0.726 | 0.399 | 1.759 | 1.10E-04 |
rs12704370 | 87430669 | A G | 0.928 | 0.462 | 1.75 | 1.70E-04 |
rs7793933 | 87416839 | T C | 0.927 | 0.462 | 1.749 | 1.70E-04 |
rs6465119 | 87402536 | G A | 0.915 | 0.452 | 1.748 | 2.10E-04 |
rs12535512* | 87220334 | T C | 0.445 | 1.694 | 1.90E-04 | |
rs13229143 | 87219481 | G C | 0.959 | 0.444 | 1.604 | 3.40E-04 |
rs13233308 | 87244960 | C T | 0.978 | 0.455 | 1.592 | 3.20E-04 |
rs2373587 | 87157466 | G C | 0.996 | 0.391 | 1.565 | 3.50E-04 |
rs2373585 | 87157706 | T C | 0.996 | 0.391 | 1.565 | 3.50E-04 |
rs10236274 | 87162341 | G A | 0.997 | 0.391 | 1.565 | 3.60E-04 |
rs2373588* | 87153160 | A G | 0.39 | 1.564 | 3.30E-04 | |
rs7787569 | 87164756 | A C | 0.994 | 0.392 | 1.539 | 3.60E-04 |
rs2285647 | 87466971 | A G | 0.851 | 0.225 | 1.539 | 1.60E-04 |
rs2141849 | 87152790 | A C | 0.988 | 0.394 | 1.527 | 3.80E-04 |
rs1978095* | 87251641 | G A | 0.233 | 1.516 | 3.40E-04 | |
rs10235853 | 87445748 | G T | 0.698 | 0.467 | 1.511 | 2.10E-04 |
rs2188526 | 87220562 | C T | 0.982 | 0.455 | 1.494 | 4.70E-04 |
rs1858923 | 87221216 | A G | 0.98 | 0.456 | 1.486 | 4.90E-04 |
rs4148751 | 87143153 | C T | 0.985 | 0.392 | 1.451 | 4.10E-04 |
rs10248420 | 87164986 | G A | 0.988 | 0.415 | 1.432 | 5.20E-04 |
rs7787082 | 87157051 | A G | 0.979 | 0.415 | 1.425 | 5.20E-04 |
rs12720464 | 87231853 | T C | 0.977 | 0.226 | 1.417 | 3.60E-04 |
rs4148750 | 87143275 | C T | 0.986 | 0.393 | 1.412 | 4.80E-04 |
rs17149699 | 87141751 | T C | 0.98 | 0.393 | 1.407 | 4.60E-04 |
rs1922243* | 87143504 | T C | 0.39 | 1.397 | 5.10E-04 | |
rs4148744 | 87150774 | A G | 0.989 | 0.399 | 1.374 | 4.40E-04 |
rs1922244 | 87145483 | A G | 0.986 | 0.399 | 1.339 | 5.30E-04 |
rs1882477 | 87151524 | G C | 0.974 | 0.415 | 1.328 | 6.40E-04 |
rs2373589 | 87151658 | T C | 0.977 | 0.413 | 1.318 | 6.60E-04 |
rs7779562 | 87144816 | C G | 0.986 | 0.4 | 1.307 | 6.20E-04 |
rs2235047 | 87138532 | C A | 0.943 | 0.38 | 1.159 | 1.16E-03 |
rs2235018 | 87199365 | C T | 0.933 | 0.211 | 1.132 | 8.60E-04 |
rs117647666 | 87374828 | A G | 0.923 | 0.208 | 1.093 | 1.09E-03 |
rs1882478* | 87137018 | C T | 0.466 | 1.056 | 1.44E-03 | |
rs6949448 | 87141814 | C T | 0.88 | 0.49 | 1.055 | 1.43E-03 |
rs2235048 | 87138511 | G A | 0.961 | 0.424 | 1.046 | 1.77E-03 |
rs4148738* | 87163049 | C T | 0.432 | 0.969 | 1.93E-03 | |
rs1045642* | 87138645 | A G | 0.411 | 0.929 | 2.63E-03 | |
rs868755* | 87189930 | T C | 0.452 | 0.715 | 5.55E-03 | |
rs3789243* | 87220886 | A G | 0.39 | 0.409 | 2.05E-02 |
P values were produced by 100000 random permutations. The SNPs marked with asterisks denote Tag SNPs. The SNPs representing independent strong associations are in bold. Physical positions of the SNPs are based on Human Reference Genome Sequence Build 37.