Figure 7. Ionic mechanism underlying response of the Hodgkin and Huxley model to a rectangular depolarizing current pulse.

The 1−h, n ⁴, and m ³ results correspond to the changes in these parameters from the beginning of the stimulus (I_stim) until a point near threshold similar to that of the optimal stimulus in Figures 2 and 3. The scales for these results are the same as in Figure 3. Note in particular changes that occur in both n ⁴ and 1−h, in contrast the results in Figure 3, as well as the significantly larger change in 1−h relative to the results in Figures 2 and 3.