Table 1. Characterization of CSC marker characteristics in established human pancreatic ductal adenocarcinoma cell lines.

	More aggressive CSChigh cells			Less aggressive CSClow cells		References
	MIA-PaCa2	AsPC-1	Capan-1	BxPc-3	Capan-2
ATCC No.	CRL-1420	CRL-1682	HRB 79	CRL-1687	HTB-80	ATCC
Source	Primary tumor	Ascites	Liver Metastasis	Primary tumor	Primary tumor	ATCC
Differentiation of primary tumor	Poor	Moderate-poor	Moderate	Well	Well	ATCC
p53 Mutation	MT	MT	MT	MT	WT	[31]
K-ras Mutation	MT	MT	MT	WT	MT	[31]
Colony-forming capacity	+++	+++	+++	+	+	[32], UOD
Spheroid-forming capacity	+++	+	++	−	−	[32], UOD
ALDH activity	+++	++	+	+	+	[32], UOD
Tumorigenic in mice	+++	+++	Yes	+	Yes	[32], UOD
E-cadherin Expression	−	++	+	+++	+++	[33],[23] UOD
Vimentin Expression	+++	+++	++	+	−	[31]

ATCC: American Tissue Culture Collection; PDAC: Pancreatic Ductal Adenocarcinoma; UOD: unpublished own data; NE: not examined; −: none; +: weak; ++: median; +++: strong; MT: mutated; WT: wild type; Yes: present, but no quantification in relation to the other cell lines available.