Figure 1. The Escherichia coli ΔnrdE and ΔnrdD mutants are defective in biofilm formation.
Biofilms of the wild-type E. coli strains (MG1655 and E2348/69) are compared to their isogenic ΔnrdE mutant in A), ΔnrdD mutant in B) and ΔnrdEΔnrdD double mutant in C). The values shown are the means of at least 4–5 independent experiments with six wells in each and the error bars represent standard deviations. Differences with respect to the wild-type strain were statistically significant for all the pairs of strains (*, P<0.05 by the Mann-Whitney test). Plots and statistics were generated using GraphPad Prism 5.0 software.