Table 3. Sequence alignment of CDR3 and FR4 from D9 VH with human JH genes.

J gene	CDR3	FR4
		***········
D9	LRYDAAY	WGQGTTVTVSS
JH1	–-AEYFQH	WGQGTLVTVSS
JH2	–-YWYFDL	WGRGTLVTVSS
JH3	––-AFDI	WGQGTMVTVSS
JH4	––-YFDY	WGQGTLVTVSS
JH5	––NWFDP	WGQGTLVTVSS
JH6	YYYYYGMDV	WGQGTTVTVSS

Note: Key residues of FR4 are marked with *.