Table 4.

mRNA expression and albumin secretion at each time-point

A) Kruskal-Wallis test
		7 days	14 days	21 days	28 days
AFP		0.0493	NS	0.0491	NS
Alb		0.0332	0.0273	0.0391	0.0394
MTP		nd	nd	nd	nd
TDO		nd	nd	nd	nd
ALB secretion		0.0125	0.0231	0.0248	0.0210
B) Kruskal Wallis test followed by Bonferroni correction
		7 days	14 days	21 days	28 days
Petri dishes vs. hLAM	AFP	0.0153	NS	0.0138	0.0040
	Alb	NS	0.0014	0.0034	0.0010
	MTP	nd	nd	nd	nd
	TDO	nd	nd	nd	nd
	Alb secr	0.0009	p < 0.0001	p < 0.0001	p < 0.0001
MatrigelTM vs. hLAM	AFP	NS	NS	NS	NS
	Alb	0.0039	NS	NS	NS
	MTP	nd	nd	nd	nd
	TDO	nd	nd	nd	nd
	Alb secr	NS	p < 0.0001	p < 0.0001	p < 0.0001
Petri dishes vs. MatrigelTM	AFP	NS	NS	NS	0.0118
	Alb	0.0003	0.0082	NS	NS
	MTP	NS	0.0026	NS	0.0127
	TDO	p < 0.0001	p < 0.0001	p < 0.0001	p < 0.0001
	Alb secr	0.0088	NS	NS	NS

(A) The Kruskal-Wallis test was used to evaluate the differences between the three supports. (B) After Bonferroni correction p < 0.016 was assumed as significant. nd: not detected; NS: not significant.Comparison between the supports.