Table 3.
ALDH7A1 immunohistochemical staining according to diagnosis and histological characteristics of the epithelial and stromal components of ovarian samples
|
Characteristics |
na |
epithelial |
stromal |
|||
|---|---|---|---|---|---|---|
| scoreb | Pc | C.I.d | scoreb | Pc | ||
|
Diagnosis |
|
|
|
|
|
|
| healthy |
5 |
0.64 ± 0.47 |
0.005* |
reference |
1.70 ± 0.45 |
0.54 |
| benign |
4 |
2.63 ± 2.29 |
|
(-2.2, 6.2) |
3.75 ± 0.50 |
|
| borderline |
3 |
4.58 ± 1.44 |
|
(-0.6, 8.5) |
3.00 ± 1.00 |
|
| invasive |
40 |
5.36 ± 2.77 |
|
(1.8, 7.7)** |
3.27 ± 2.67 |
|
|
Histology |
|
|
|
|
|
|
| serous |
18 |
4.57 ± 3.09 |
0.34 |
|
2.87 ± 2.53 |
0.08 |
| mucinous |
8 |
6.44 ± 2.46 |
|
|
5.43 ± 1.86 |
|
| endometrioid |
8 |
5.88 ± 2.58 |
|
|
1.70 ± 1.75 |
|
| clear cell | 5 | 6.20 ± 1.79 | 3.25 ± 4.03 | |||
a Number of cases.
b Immunohistochemistry staining score expressed as mean ± SD.
c P-value, ANOVA test of equal means among the four groups (* equal population variances assumption did not meet, corresponding p-value using Kruskal-Wallis test for equal medians was displayed).
d Two-sided 95% confidence interval (C.I.) for the difference in means, Dunnett’s post-hoc test compared to value in healthy (in Diagnosis group) or clear cell (in Histology group) as the “reference” group. Dunnett’s test was performed only when the ANOVA or Kruskal-Wallis result was significant (p < 0.05).
** Significant based on Dunnett’s test (family error rate set to 0.05).