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. 2012 Sep 26;7(9):e45806. doi: 10.1371/journal.pone.0045806

Table 1. Inhibition of enzyme activities of respiratory complexes.

% inhibition
LY294002 Akt inhibitor IV
RCI 14.9±0.87# 66.5±6.99#
RCII 33.7±9.18** 38.6±7.89**
RCIII 26.8±8.25** 38.1±1.01#
RCIV 21.3±4.41** 42.9±6.06#

Activities of respiratory complexes I to IV were inhibited by LY294002 (inhibitor of PI3K and mTOR) and Akt inhibitor IV. Values are expressed as % inhibition compared to untreated controls.

**

p<0.01 and

#

p<0.005 for n = 3.