Table 2.
Distributions of IL17A genotypes and gene mathylations
| |
DAPK |
CDH1 |
||||
|---|---|---|---|---|---|---|
| Unmethylated | methylated | p value* | unmethylated | methylated | p value* | |
| number of subjects |
205 |
196 |
|
252 |
149 |
|
| mean age ± SD |
59.3 ± 13.6 |
60.8 ± 13.9 |
NS |
60.1 ± 14.1 |
59.9 ± 13.2 |
NS |
| male : female |
118 : 87 |
112 : 84 |
NS |
145 : 107 |
85 : 64 |
NS |
|
H. pylori positive rate |
104/205 |
137/196 |
<0.0001 |
131/252 |
110/149 |
<0.0001 |
| -197 G > A |
|
|
|
|
|
|
| GG |
86 |
69 |
98 |
57 |
|
|
| GA |
99 |
105 |
128 |
76 |
|
|
| AA |
19 |
22 |
26 |
15 |
|
|
| (unknown) |
1 |
0 |
0 |
1 |
|
|
| A allele frequency |
33.6% |
38.0% |
NS |
35.7% |
35.8% |
NS |
| *1249 C > T |
|
|
|
|
|
|
| CC |
167 |
173 |
0.023a |
210 |
130 |
|
| CT |
28 |
14 |
|
28 |
14 |
|
| TT |
10 |
6 |
11 |
5 |
|
|
| (unknown) |
0 |
3 |
|
3 |
0 |
|
| T allele frequency11. | 7% | 6.7% | 0.020 | 10.0% | 8.2% NS | |
*: unmethylated vs. methylated.
a: frequency of *1249 CC genotype.