Table 3.
Association between IL17A -197 G > A polymorphism and gene methylation
| CIHM (DAPKorCDH1) | GG | GA | AA | unknown | A carrier vs. GG; OR (95%CI) | p value |
|---|---|---|---|---|---|---|
| unmethylated (153) |
65 |
74 |
14 |
0 |
reference |
- |
| methylated (248) |
90 |
130 |
27 |
1 |
1.33 (0.870-2.04) |
0.19 |
|
DAPK |
|
|
|
|
|
|
| unmethylated (205) |
86 |
99 |
19 |
1 |
reference |
- |
| methylated (196) |
69 |
105 |
22 |
0 |
1.37 (0.907-2.08) |
0.13 |
|
CDH1 |
|
|
|
|
|
|
| unmethylated (252) |
98 |
128 |
26 |
0 |
reference |
- |
| methylated (149) | 57 | 76 | 15 | 1 | 1.04 (0.676-1.60) | 0.86 |
by logistic regression analysis after adjustment for age, gender and H. pylori infection status.
( ): number of subjects.