Table 4.
Association between IL17A *1249 C > T polymorphism and gene methylation
| CIHM (DAPKorCDH1) | CC | CT | TT | unknown | T carrier vs. CC; OR (95%CI) | p value |
|---|---|---|---|---|---|---|
| unmethylated (153) |
124 |
20 |
9 |
0 |
reference |
- |
| methylated (248) |
216 |
22 |
7 |
3 |
0.611 (0.343-1.09) |
0.096 |
|
DAPK |
|
|
|
|
|
|
| unmethylated (205) |
167 |
28 |
10 |
0 |
reference |
- |
| methylated (196) |
173 |
14 |
6 |
3 |
0.513 (0.282-0.933) |
0.028 |
|
CDH1 |
|
|
|
|
|
|
| unmethylated (252) |
210 |
28 |
11 |
3 |
reference |
- |
| methylated (149) | 130 | 14 | 5 | 0 | 0.856 (0.466-1.57) | 0.62 |
by logistic regression analysis after adjustment for age, gender and H. pylori infection status.
( ): number of subjects.