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. 2012 Jul 24;13:59. doi: 10.1186/1471-2350-13-59

Table 5.

Risk of IL17A plymorphisms for gene methylation in the subjects older than 60 years old

CIHM (DAPKorCDH1)
 IL17A -197 G > A
GG
GA
AA
unknown
A carrier vs. GG; OR (95%CI)
p value
 unmethylated (83)
38
39
6
0
reference
-
 methylated (143)
46
79
18
0
1.80 (1.01-3.19)
0.046
 IL17A *1249 C > T
CC
CT
TT
unknown
T carrier vs. CC; OR (95%CI)
p value
 unmethylated (83)
63
15
5
0
reference
-
 methylated (143)
124
13
5
1
0.463 (0.224-0.959)
0.038
DAPK
 
 
 
 
 
 
 IL17A -197 G > A
GG
GA
AA
unknown
A carrier vs. GG; OR (95%CI)
p value
 unmethylated (103)
44
50
9
0
reference
-
 methylated (123)
40
68
15
0
1.57 (0.897-2.75)
0.11
 IL17A *1249 C > T
CC
CT
TT
unknown
T carrier vs. CC; OR (95%CI)
p value
 unmethylated (103)
79
19
5
0
reference
-
 methylated (123)
108
9
5
1
0.427 (0.204-0.893)
0.024
CDH1
 
 
 
 
 
 
 IL17A -197 G > A
GG
GA
AA
unknown
A carrier vs. GG; OR (95%CI)
p value
 unmethylated (145)
60
71
14
0
reference
-
 methylated (81)
24
47
10
0
1.76 (0.958-3.22)
0.068
 IL17A *1249 C > T
CC
CT
TT
unknown
T carrier vs. CC; OR (95%CI)
p value
 unmethylated (145)
116
22
6
1
reference
-
 methylated (81) 71 6 4 0 0.590 (0.263-1.32) 0.20

by logistic regression analysis after adjustment for age, gender and H. pylori infection status.

( ): number of subjects.