Table 4.
Regression analysis of eGFR with interaction between homocysteine and MTHFR C677T genotype
| |
Males |
Females |
||||
|---|---|---|---|---|---|---|
| β | SE | P | β | SE | P | |
| CT |
−3.54 |
3.12 |
0.26 |
−0.83 |
2.30 |
0.72 |
| TT |
−9.39 |
3.16 |
0.003 |
−0.79 |
2.48 |
0.75 |
| log(Hcy) |
−6.73 |
1.15 |
5.7x10-9 |
−7.10 |
0.89 |
1.4x10-15 |
| CT:log(Hcy) |
1.52 |
1.32 |
0.25 |
0.42 |
1.04 |
0.69 |
| TT:log(Hcy) | 3.91 | 1.29 | 0.0024 | 1.04 | 1.08 | 0.34 |
Regression was done with adjustment for age, BMI, systolic and diastolic blood pressures (coefficients not shown). Log(Hcy) was the natural log of plasma homocysteine in μmol/L. β regression coefficient, SE standard error, eGFR was in unit of ml/min/1.73 m2.