Table 2.
Changes of Symptoms and Signs After Allogeneic Serum Eye Drops in Patients with Chronic Ocular Graft-Versus-Host Disease
| Before treatment | Four weeks after allogeneic serum eye drops | P-valuea | |
|---|---|---|---|
| OSDI score | 32.5±8.9 | 20.6±5.6 | <0.005 |
| tBUT(s) | 2.9±1.9 | 4.4±2.2 | 0.04 |
| Schirmer I test (mm) | 1.7±2.3 | 2.4±1.9 | 0.32 |
| Tosm (mOSM) | 311.1±15.9 | 285.1±5.8 | <0.005 |
| Corneal staining score | 2.5±0.6 | 1.8±0.7 | <0.005 |
| IC grade | 3.4±0.5 | 2.4±0.6 | <0.005 |
| Goblet cell density (cells/mm2) | 90.6±44.1 | 122.6±49.2 | <0.005 |
a
Statistics: paired t-test.
OSDI score, Ocular Surface Disease Index score; tBUT, tear breakup time; Tosm, tear osmolarity; IC, impression cytology; mOSM, milliosmol.