Table 1.

Effect of Recalibration and Filtering on Recorded Continuous Glucose Monitoring of Hypoglycemia for the Entire Cohort and per Patient

	Original CGM	Recalibrated CGM	Recalibrated and filtered CGM	Filtered valid ISIGthen recalibrated CGM
Overall cohort results
Number of hypoglycemic events	161	193	131	146
Duration (% of CGM record<2.6 mmol/L)	2.2	2.6	2.5	2.6
Hypoglycemic index (μmol/L)	4.9	7.1	6.9	6.8
Hypoglycemia events
Between 2.4 and 2.6 mmol/L	87	87	51	61
Between 2.2 and 2.4 mmol/L	35	40	35	34
Between 2.0 and 2.2 mmol/L	18	38	23	30
<2.0 mmol/L	21	28	22	21
Number of patients with no hypoglycemia	25	19	21	19
Per-patient results
Number of hypoglycemic events	1 (0–3)	1 (0–4)	1 (0–3)	1 (0–3)
Duration (% of data hypoglycemic)	0.1 (0.0–1.0)	0.5 (0.0–2.4)	0.5 (0.0–2.3)	0.6 (0.0–2.4)
Hypoglycemic index (μmol/L)	2.1 (0.7–6.8)	0.8 (0.0–7.1)	0.5 (0.0–6.0)	3.9 (0.7–9.5)
Hypoglycemic state (no. of patients)
Original hypoglycemia→hypoglycemia	—	24	22	23
Original hypoglycemia→no hypoglycemia	—	1	3	2
Originally no hypoglycemia→hypoglycemia	—	7	7	8
Originally no hypoglycemia→no hypoglycemia	—	18	18	17

Data are median (interquartile range) values where applicable.

CGM, continuous glucose monitoring; I_SIG, electrical current detected by the monitor from the sensor.