Table 4.
Non-pregnant control | Non-pregnant restricted | |||||||
---|---|---|---|---|---|---|---|---|
Arteries | Uterine | Mesenteric | Renal | Femoral | Uterine | Mesenteric | Renal | Femoral |
OD (μm) | 473 ± 9 | 403 ± 15 | 522 ± 12 | 627 ± 5 | 479 ± 6 | 394 ± 6 | 540 ± 18 | 644 ± 7 |
ID (μm) | 417 ± 11 | 377 ± 15 | 455 ± 12 | 539 ± 7 | 442 ± 7 | 364 ± 6 | 469 ± 17 | 559 ± 8 |
WT (μm) | 28 ± 2 | 14 ± 1 | 34 ± 1 | 44 ± 3 | 19 ± 1† | 16 ± 1 | 36 ± 2 | 43 ± 2 |
M-L ratio | 0.068 ± 0.007 | 0.035 ± 0.002 | 0.075 ± 0.005 | 0.081 ± 0.006 | 0.042 ± 0.004 † | 0.041 ± 0.003 | 0.077 ± 0.005 | 0.077 ± 0.004 |
Pregnant control | Pregnant restricted | |||||||
---|---|---|---|---|---|---|---|---|
Arteries | Uterine | Mesenteric | Renal | Femoral | Uterine | Mesenteric | Renal | Femoral |
OD (μm) | 678 ± 10# | 447 ± 23# | 543 ± 21 | 652 ± 6 | 689 ± 22# | 441 ± 20# | 573 ± 28 | 631 ± 12 |
ID (μm) | 617 ± 11# | 416 ± 23# | 474 ± 17 | 560 ± 8 | 626 ± 21# | 414 ± 21# | 504 ± 27 | 551 ± 11 |
WT (μm) | 31 ± 3 | 17 ± 1 | 35 ± 3 | 47 ± 3 | 32 ± 2 § | 14 ± 1 | 36 ± 3 | 40 ± 3 |
M-L ratio | 0.050 ± 0.005 ‡ | 0.039 ± 0.005 | 0.073 ± 0.006 | 0.083 ± 0.006 | 0.050 ± 0.004 | 0.034 ± 0.003 | 0.070 ± 0.006 | 0.073 ± 0.006 |
Outside diameter (OD), internal diameter (ID), wall thickness (WT) and media-to-lumen (M-L) ratio in arteries from non-pregnant and pregnant (E20) animals. Values are expressed as means ± SEM; uterine (n = 8–10/group); mesenteric (n = 6–10/group); renal (n = 8–10/group); femoral (n = 6–10/group). #P < 0.05 vs. non-pregnant (main effect). †P < 0.05 vs. non-pregnant Control (following significant interaction). §P < 0.05 vs. non-pregnant Restricted (following significant interaction). ‡P < 0.05 vs. non-pregnant Control (following significant interaction). — indicates no response.