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The morphology of mouse ESCs and iPS cells upon neuronal differentiation. Phase-contrast images demonstrate 8-day-old EBs derived from mouse HM1 ES (A) and SB-mediated iPS cells (B). The cells were induced to differentiate into the neuronal lineage using RA. A neuron-like phenotype, such as neurite processes, can be observed 2 days after EB dissociation in both ESCs (C) and iPS (D) cells. Scale bars, 500 μm (A, B) and 100 μm (C, D).
