Fig. 3.
CE accumulation in small intestine of HSLiKO mice fed HF/HC diet. TC, FC and CE concentrations in jejunum of mice fed (A) chow or (B) HF/HC diet for 4 weeks. Data represent mean values (n = 4–5) ± SEM. *p ≤ 0.05. (C–E) Mice were gavaged with 100 μl corn oil containing 2 μCi [3H]cholesterol and 500 μg cholesterol. Radioactivity in (C) CE and (D) FC fractions per g tissue in the whole small intestine, duodenum, jejunum and ileum was determined by liquid scintillation counting. (E) Relative distribution of radioactive cholesterol in CE and FC fractions 4 h after gavaging. Data represent mean values (n = 6) ± SEM. *p ≤ 0.05, **p ≤ 0.01. (F, G) Mice were fed chow or HF/HC diet for 4 weeks and jejunal (F) TG and (G) DG were determined. Data represent mean values (n = 6–8) ± SEM.