Fig. 6.

Histological changes of the annulus needle puncture model. Overview of histological changes in the intervertebral discs by pre-operative Hematoxylin and eosin staining, 8 and 12 weeks after puncture in Bach 1−/− mice (a–f) and wild-type mice (g–l). The histological changes are clear in both groups, and less degenerative change can be observed in Bach 1−/− mice at 8 and 12 weeks after puncture. Scale bar = 200 μm (a–c, g–i) and Scale bar = 40 μm (d–f, j–l)