Table 3.

Differential diagnosis of erythroderma presenting in the neonatal period.

INFECTIONS

Staphylococcal scalded skin syndrome (SSSS)

Congenital cutaneous candidiasis

IMMUNODEFICIENCY

Graft-versus-host disease (GvHD) with underlying SCID

Omenn’s syndrome

ICHTHYOSES

Non-syndromic ichthyoses (non-bollous ichthyoses, bollous ichthyoses)

Syndromic ichthyoses (Netherton’s syndrome, Conradi–Hünermann syndrome)

METABOLIC DISEASES

Multiple carboxylase deficiencies

Essential fatty acid deficiency

DRUGS

Ceftriaxone

Vancomycin

OTHER SKIN PATHOLOGIES

Infantile seborrheic dermatitis

Atopic dermatitis

Psoriasis

Cutaneous mastocytosis