. 2012 Aug 31;3(3):245–251.

Table 1.

Observed genotype and allele frequencies in subjects with chronic tinnitus (N=240) and tests for allelic association. Data from nine Caucasian control populations were used with Bonferroni corrections.

dbSNP identifier	gene	2N	major:minor allele (1:2)	predicted protein variant	genotypes (11:12:22)	MAF in chronic tinnitus	MAF in unrelated Caucasian controls (N)		p _association (p _corrected)
rs2049046	BDNF	480	A:T	-	69:105:66	0.494	0.467 (379)^a		n.s.
							0.481 (128)	[51]	n.s.
							0.476 (287)	[52]	n.s.
rs6265	BDNF	480	G:A	V66M	155:76:9	0.196	0.191 (4299)^b		n.s.
							0.203 (379)^a		n.s.
							0.137 (128)	[51]	0.05 (0.74)
							0.190 (2100)	[53]	n.s.
							0.213 (839)	[54]	n.s.
							0.185 (664)	[55]	n.s.
							0.218 (333)	[56]	n.s.
							0.175 (2184)	[57]	n.s.
rs1110149	GDNF	480	G:C	-	62:121:57	0.490	0.410 (379)^a		0.007 (0.10)
rs884344	GDNF	480	T:G	-	125:101:14	0.269	0.236 (379)^a		n.s.
rs3812047	GDNF	476	G:A	-	178:52:8	0.143	0.144 (379)^a		n.s.

all alleles refer to the transcribed strand, MAF = minor allele frequency.

reference population of European ancestry from the 1000 Genomes Project, July 2010 data release (URL: http://www.1000genomes.org), accessed July 2012;

reference population of European ancestry from the NHLBI GO Exome Sequencing Project. Data retrieved with the Exome Variant Server (URL: http://evs.gs.washington.edu/EVS/), accessed July 2012.