Table 1.
Various probiotic strains and their applications in different types of cancer and side effects associated with cancer.
Sr No | Strain | Indication | Results | References |
---|---|---|---|---|
(1) | L. rhamnosus GG + B. lactis Bb12 (10B each with inulin) | Polypectomized and colon cancer patients | Increased L. rhamnosus and B lactis in feces, reduction in C perfringens, prevents increased secretion of IL-2 in polypectomized patients, increased production of interferon-γ in cancer patients. | [107] |
(2) | L. casei Shirota 30B daily | Recurrence of superficial bladder cancer | Significant reduction in primary multiple and recurrent single tumors | [108] |
(3) | L. casei Shirota | Preventive effect on bladder cancer | Significant reduction in risk of bladder cancer | [109] |
(4) | L. casei LC9018 | Cervical cancer | Reduced immunity against tumor induction | [110] |
(5) | L. plantarum CGMCC No 1258, L. acidophilus LA-11, B. longum BL-88. Daily dose of 2.6∗1014CFU | Barrier function and post-operative infectious complications in Colorectal cancer surgery | Improvement in the integrity of gut mucosal barrier and decrease in infectious complications | [111] |
(6) | L. acidophilus and B. bifidum 1B CFU each | Diarrhea during radiotherapy in cervical cancer | Reduction in incidence of diarrhea and better stool consistency. | [112] |
(7) | VSL#3 | Radiation induced diarrhea | Less diarrhea, improvement in daily bowel movements | [113] |
(8) | L. rhamnosus GG 10 to 20B daily for 24 weeks | Diarrhea related to chemotherapy of colorectal cancer | Patients had less grade 4 or 4 diarrhea, less abdominal discomfort, needed less hospital care and had fewer chemo dose reduction due to bowel toxicity. | [114] |