Figure 7.

Cyclin D1 protein concentrations in cell lysates after exposure to C2, AL6, C6, and C8 or with vehicle alone for 144 hours in (A) endothelial and (B) pancreatic cancer cell lines. (C) TSP-1 gene expression (2^-ΔΔCt) in endothelial cell lines (HUVEC and HMVEC-d) exposed to AL6 or to vehicle alone for 144 hours. (D) TSP-1 secretion in the conditioned media of HMVEC-d and HUVECs exposed to C2, AL6, C6, and C8 or to vehicle alone for 144 hours. TSP-1 concentrations in conditioned media were measured by ELISA and normalized to total protein concentration. Columns and bars, mean values ± SD, respectively. *P < .05 versus vehicle-treated controls.