Table 1.
Ag nanoparticle | Stock solvent | Ag concentration in stock (mg/mL) | Ag concentration in infusion media (μg/ml) | Diameter (nm) | Zeta Potential (mV) | ||
---|---|---|---|---|---|---|---|
Target | Measured | TEM | DLS | ||||
Silver citrate (Biopure) | Aqueous 2mM citrate | 1.0 | 0.855 | 0.84 ± 0.014 | 19.2 | NA | −36.8 |
Silica-coated silver | Milli-Q water | 4.66 | 0.855 | 0.48 ± 0.010 | 40.5 | 146.7 | 25.4 |
NA=Not applicable. The manufacturer, Nanocomposix, uses a a DLS instrument with a HeNe laser operating at 632.8 nm, and silver nanoparticles with physical diameters less than ~25 nm do not scatter enough photons for use to obtain reasonable signal to noise ratios to determined the hydrodynamic diameter.