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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Pflugers Arch. 2012 Sep 12;464(4):415–423. doi: 10.1007/s00424-012-1150-7

Fig. 7.

Fig. 7

Effects of Ac-SDKP on ET-1-stimulated collagen production in controls and NSC-87877-pretreated fibroblasts. Basal collagen production was similar in both the controls and NSC-87877-treated cells. Ac-SDKP significantly inhibited ET-1-stimulated collagen production in the controls but not in the SHP-2-inhibited cells, suggesting that Ac-SDKP inhibits ET-1-stimulated collagen production through mechanisms related to SHP-2. * p < 0.005, ET-1 vs control; † p < 0.005, Ac-SDKP plus ET-1 vs ET-1 alone (n = 4 per group)