Table 3.

Distribution of the 701 individuals^§ according to the presence of microcytosis, hypochromia and/or anemia.

Group	N	Genotype
		αα/αα	α3.7/αα or -α3.7/-α3.7
(I) With microcytosis and/or hypochromia with anemia	33	20 (60.6%)	13 (39.4%)
(II) With microcytosis and/or hypochromia without anemia	101	56 (55.4%)	45 (44.6%)
(III) Without microcytosis and/or hypochromia with anemia	49	48 (98.0%)	1 (2.0%)
(IV) Without hematological alterations	518	499 (96.3%)	19 (3.7%)

^§10 samples with normal genotype and 2 with α⁺-thalassemia were excluded due to hemolysis and/or coagulation.

Risk relative (RR) to alpha-thalassemia among the groups: [RR(Confidence Interval), p value].

Group I x Group II: [0.86 (0.46–1.57), p = 0.6054] Group II x Group III: [1.82 (1.51–2.18), p < 0.0001].

Group I x Group III: [3.16 (2.13–4.69), p < 0.0001] Group II x Group IV: [6.97 (5.19–9.34), p < 0.0001].

Group I x Group IV: [10.54 (5.79–19.21), p < 0.0001] Group III x Group IV: [0.57 (0.08–3.92), p = 0.5677].