Figure 7.

Liver cytosolic cytokine levels. Cytokine levels were measured in cytosolic extracts of liver harvested at multiple times after burn injury using a 24-plex assay (n = 5–10 separate animals for each group per time point). Although most of the 24 cytokines measured showed significant changes between the two groups over time (two-way ANOVA), we report results for eight representative cytokines. Data from hyperglycemic and control groups were compared over time by two-way ANOVA (*). Changes within each group were analyzed by one-way ANOVA with post hoc correction and compared with sham, no burn (# for hyperglycemic group and × for control group). Differences at each time point between hyperglycemic and control animals were analyzed by Tukey t test (¶).