Table 4.

Frequency of hair and nail features (n=112) in reported trichothiodystrophy patients

	Patients No. (%)
Hair feature	112 (100)
Brittle hair or hair shaft abnormality	108 (96)
Brittle hair	98 (88)
Hair shaft abnormality	76 (68)
Tiger tail	82 (73)
Decreased sulfur or cystine	79 (71)
Sparse hair	54 (48)
Alopecia	44 (39)
Hair loss with fever or infection	8 (7)
Dry hair	24 (21)
Fine hair	16 (14)
Slow growing hair	8 (7)
Long hair	5 (4)
Nail feature	70 (63)
Onychodystrophy*	41 (37)
Brittle nails	16 (14)
Hypoplasia	15 (13)
Koilonychia	13 (12)
Splitting (onychoschizia); peeling	8 (7)
Ridging	7 (6)
Other†	3 (3)
Normal nails; not reported	14 (13); 28 (25)
Total	112 (100)

^*We collated reports of dysplasia, dystrophic nails, thickening and yellow discoloration as onychodystrophy.

^†Slow growing nails (2 patients) and soft nails (1).