Figure 2.

MDCBs with bacterial cells in control cultures and cultures treated with GCLRP. (A) Control cultures show MDCBs with bacterial cells associated with their surface only. (B) Cultures treated 4 h with 10 nM GCLRP contain numerous MDCBs that internalized the fluorescently labeled bacterial cells indicating increased phagocytic activity (arrows indicate phagocytosis of the bacterial cells).

Abbreviations: MDCBs, monocyte-derived cells of the brain; GCLRP, peptide mimetic of a ligand of C-type lectin receptor.