Figure 4.

Characterization of macrophagal populations in steady state according to selected cell surface markers. (A–E) Characterization of macrophagal populations in steady state according to selected cell surface markers. Dendritic cells show fairly consistent levels of expression across the markers, while inactive and PMa show significantly variable levels of the same markers. (F–H) Levels of selected surface markers on inactive and PMa are significantly increased by day 7 of GCLRP treatment while afterward levels fall.

Abbreviations: CD, cluster of differentiation; MHCII, major histocompatibility complex II; GCLRP, peptide mimetic of a ligand of C-type lectin receptor; PMa, patrolling macrophages.