Figure 7.

MHCII⁺ CD11c⁺ positive monocytes (blood precursors of DCs) in animals with tumors treated with GCLRP compared to animals with tumors but no treatment. For MHCII⁺ CD11c⁺ positive monocytes (blood precursors of DCs), animals with tumors treated with GCLRP compared to animals with tumors but no treatment showed (A) increased number of MHCII⁺ CD11c⁺ positive monocytes in the blood, and significantly upregulated expression of key surface markers (B–E).

Abbreviations: MHCII, major histocompatibility complex II; CD, cluster of differentiation; DCs, dendritic cells; GCLRP, peptide mimetic of a ligand of C-type lectin receptor.