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. 2012 Sep 17;4:309–323. doi: 10.2147/CMAR.S33248

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© 2012 Kushchayev et al, publisher and licensee Dove Medical Press Ltd.

This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.

PMC Copyright notice

FACS analysis of MDCBs within the glioma. (A) Dot-plots represent population of the CD115⁺ cells in control and GCLRP treated animals. Analysis of MDCB within glioma; (B) GCLRP treatment was associated with increased MDCBs within glioma; (C) proportional redistribution of microglial and macrophagal populations in the tumor area under GCLRP treatment; and (D) proportional redistribution of macrophagal subsets where DCs predominated in control samples, but PMa predominated in GCLRP treated samples.

Abbreviations: FACS, fluorescence-activated cell sorting; MHCII, major histocompatibility complex; MDCBs, monocyte-derived cells of the brain; CD, cluster of differentiation; GCLRP, peptide mimetic of a ligand of C-type lectin receptor; DCs, dendritic cells; PMa, patrolling macrophages.