Table 1.

Characteristics of the study subjects

ID	Non-IBDa	CD1b	CD2	CD3	CD4
Diagnosis	Normal	Colitis	Colitis	Ileitis	Ileocolitis
Symptom duration (months)	3	5	2	7	2
Age	41	52	44	38	39
Sex	M	M	M	F	M
Smoking	N	N	Y	Y	N
NOD2 mutation	–	–	–	–	–
HBI	3	6	8	5	9
Calprotectinc	5	477	32	29	354
CRPd	7	7	7	7	21
Symptoms	Abdominal pain, temporary loose stools	Loose stools, no abdominal pain or bloody stools	Loose stools, no abdominal pain or bloody stools	Abdominal pain in lower right quadrant, no loose stools	Episodic abdominal pain with loose, bloody stools
Macroscopic findings	Normal	Continuous diffuse inflammation with erythema, edema, and fragile mucosa throughout the colon	Aphtous lesions from the ascending colon to the sigmoid, but not in the ileum or the rectum	Aphtous lesions in the terminal ileum	Stenosis of the ileocoecal valve
Microscopic findings	Normal	Patchy chronic active inflammation	Light grade of patchy inflammation throughout the colon	Light chronic active inflammation	Chronic active inflammation of the ileocoecal valve, widespread light chronic active inflammation throughout the colon
Granuloma	No	Yes	No	No	No

Notes:

^aNon-IBD control;

^bCrohn’s disease.