Table 2.
n | Hb* (g/dL) | p-value | MCV* (fl) | p-value | Fetal Hb* (%) | p-value | ||
Mean ±SD [95% CI] | Mean ±SD [95% CI] | Mean ±SD [95% CI] | ||||||
Gender | ||||||||
Male | 48 | 8.2 ± 1.2 [7.9-8.6] | 80.8 ± 12.3 [77.3-84.4] | 12.0 ± 8.3 [9.5-14.5] | ||||
Female | 48 | 8.9 ± 1.3 [8.5-9.2] | < 0.05 | 81.2 ± 9.4 [78.4-83.9] | > 0.05 | 12.3 ± 5.9 [10.4-14.2] | > 0.05 | |
Age group | ||||||||
0-3 years old | 62 | 8.7 ± 1.4 [8.3-9.0] | 78.4 ± 10.3 [75.8-81.0] | 13.1 ± 7.6 [10.9-15.2] | ||||
3-6 years old | 34 | 8.3 ± 1.2 [7.8-8.7] | > 0.05 | 85.7 ± 10.6 [82.0-89.4] | < 0.05 | 10.7 ± 6.3 [8.5-12.9] | > 0.05 | |
α-Thalassemia | ||||||||
αα/αα | 72 | 8.5 ± 1.2 [8.2-8.8] | 83.7 ± 9.0 [81.6-88.5] | 12.5 ± 7.1 [10.7-14.2] | ||||
-α/αα or -α/-α | 19 | 8.9 ± 1.7 [8.1-9.7] | > 0.05 | 71.7 ± 11.9 [66.0-77.4] | < 0.05 | 12.5 ± 8.0 [8.1-16.9] | > 0.05 | |
β- globin haplotype | ||||||||
Bantu/Bantu | 39 | 8.0 ± 1.0 [7.6-8.3]# | 84.8 ± 9.7 [81.7-87.9]# | 11.9 ± 5.3 [10.2-13.8]# | ||||
Bantu/Benin | 32 | 8.7 ± 1.2 [8.2-9.1] | < 0.05 | 83.1 ± 7.3 [80.4-85.7] | > 0.05 | 16.1 ± 8.1 [12.9-19.2] | < 0.05 | |
Bantu/CI | 7 | 10.5 ± 0.5 [10.0-11.0] | 71.8 ± 8.6 [63.8-79.9] | 4.1 ± 3.4 [0.5-7.8] | ||||
Bantu/Atypical | 9 | 8.5 ± 1.5 [7.4-9.7] | 74.0 ± 10.7 [65.8-82.3] | 7.9 ± 3.9 [4.7-11.2] | ||||
Benin/Benin | 2 | 7.8 ± 1.5 | 86.6 ± 14.6 | 15.9 ± 14.4 | ||||
Benin/CI | 2 | 10.4 ± 0.6 | 66.2 ± 21.5 | - | ||||
Benin/Atypical | 2 | 9.5 ± 1.2 | 67.7 ± 15.9 | 5.3 ± 0.7 | ||||
Atypical/CI | 2 | 8.3 ± 0.6 | 80.9 ± 4.2 | 4.2 ± 0.5 |
*Mean value of mean of each case;
# between Bantu/Bantu and Bantu/Benin groups. Analysis by student t-test. Hb: hemoglobin; MCV: mean corpuscular volume.