Table 3.
β-globin haplotype | α- thalassemia | |||||||
Events | Bantu/Bantu | Bantu/Benin | αα/αα | -α/αα and -α/-α | ||||
n = 39 | n = 32 | n = 72 | n = 19 | |||||
n (%) | n (%) | n (%) | n (%) | |||||
Painful events | 16 (41.0) | 12 (37.5) | 32 (35.9) | 8 (42.1) | ||||
Splenic sequestration | 21 (53.8) | 17(53.1) | 34 (47.2) | 9 (47.3) | ||||
Hemolytic crises | 25 (64.1) | 25 (78.1) | 46 (63.4) | 10 (52.6) | ||||
Hand-foot syndrome | 16 (41.0) | 12 (37.5) | 29 (40.2) | 4 (21.1) | ||||
Infection | 35 (89.7) | 27 (84.3) | 66 (91.7) | 14 (73.6)* | ||||
Acute chest syndrome | 2(5.1) | 6 (18.7) | 6 (8.3) | 3 (15.8) |
* p-value < 0.05