Table 1.
Lung function parameters, arterial blood gases, and FOT indices at baseline and after intrapulmonary percussive ventilation treatment
|
Pre
|
Post
|
P value | |||
|---|---|---|---|---|---|
| Mean value | SD | Mean value | SD | ||
| VC (L) | 2.75 | 0.43 | 2.81 | 0.41 | 0.273 |
| FEV1 (%p) | 39.49 | 23.62 | 40.27 | 23.23 | 0.225 |
| FEV1/VC (%) | 34.00 | 13.44 | 33.80 | 13.75 | 0.564 |
| TLC (%p) | 169 | 62 | 168 | 57 | 1 |
| MEF 25 (L/s) | 0.13 | 0.05 | 0.13 | 0.05 | 0.18 |
| MEF 50 (L/s) | 0.34 | 0.23 | 0.35 | 0.27 | 0.785 |
| RV (L) | 4.86 | 2.19 | 4.61 | 2.34 | 0.686 |
| DLCO (mmol/min/kPa) | 2.99 | 1.49 | 3.25 | 1.76 | 0.138 |
| DLCO/VA (mmol/min/kPa/L) | 0.75 | 0.43 | 0.80 | 0.46 | 0.066 |
| MIP (kPa) | 6.88 | 0.61 | 6.84 | 1.02 | 1 |
| MEP (k Pa) | 11.54 | 1.14 | 10.22 | 2.72 | 0.068 |
| Borg Dyspnea | 4 | 0.71 | 3.4 | 0.89 | 0.083 |
| pH | 7.47 | 0.04 | 7.47 | 0.03 | 0.68 |
| PaO2 (mmHg) | 74.88 | 16.10 | 76.52 | 10.30 | 0.893 |
| PaCO2 (mmHg) | 39.32 | 6.50 | 39.60 | 5.98 | 0.343 |
| HCO3− (mmol/L) | 27.98 | 4.39 | 28.22 | 4.75 | 0.343 |
| SaO2 (%) | 95 | 3.00 | 96 | 1.00 | 0.066 |
| Raw (kPa.s/L) | 1.07 | 0.30 | 1.27 | 0.34 | 0.109 |
| sRaw (kPa.s) | 8.30 | 3.39 | 10.22 | 3.86 | 0.109 |
| S_R6 (hPa.s/L) | 4.79 | 0.61 | 5.40 | 0.89 | 0.080 |
| S_R8 (hPa.s/L) | 4.18 | 0.36 | 4.61 | 0.79 | 0.080 |
| L_R6 (hPa.s/L) | 5.88 | 0.85 | 6.27 | 1.35 | 0.465 |
| L_R8 (hPa.s/L) | 5.28 | 0.81 | 5.37 | 0.82 | 0.715 |
Note: Significance P < 0.05.
Abbreviations: VC, vital capacity; FOT, forced oscillation technique; %p, expressed as percentage of the predicted value; FEV1, forced expiratory volume in 1 second; TLC, total lung capacity; MEF 25, maximal expiratory flow when 75% of FVC is expired; MEF 50, maximal expiratory flow when 50% of FVC is expired; RV, residual volume; VA, alveolar volume; DLCO, diffusing capacity for carbon monoxide; DLCO/VA, Kroch factor; MIP, maximal inspiratory pressure; MEP, maximal expiratory pressure; Raw, airway resistance; sRaw, specific airway resistance; S_R6, S_R8, Fot resistance at 6 Hz and 8 Hz, respectively in the sitting position; L_R6, L_R8, Fot resistance at 6 Hz and 8 Hz, respectively in the supine position.