TABLE 2.
Item | Mittendorf, 199729, 30 | Crowther, 200331 | Magpie, 200732 | Marret, 200733, 34 | Rouse, 200835 | |
---|---|---|---|---|---|---|
Tocolytic arm |
Neuroprotective arm |
|||||
Randomization | Yes | Yes | Yes | Yes | Yes | Yes |
Method to generate randomization clear and appropriate |
Yes | Yes | Yes | Yes | Yes | Yes |
Double blind | No | Yes | Yes | Yes | Yes | Yes |
Methods for blinding appropriate | No | Yes | Yes | Yes | Yes | Yes |
Method of allocation concealmenta | No | Unreported | Adequate | Adequate | Adequate | Adequate |
Description of withdrawal or dropout |
No | No | Yes | Yes | Yes | Yes |
Completeness of follow-up of randomized fetuses (%)b |
Unreported | Unreported | 98.9 | 47.4c | 98.5 | 95.6 |
Total score | 2 | 4 | 8 | 7 | 8 | 8 |
Yes=1 point, No=zero points; Scores: 0=lowest quality, 8=highest quality
Adequate=2 points, no concealment of allocation or inadequate method or unreported=zero points
Follow-up ≥95%=1 point, follow-up <95% or unreported=zero points
For fetuses of all gestational ages and undelivered at randomization