. 2012 Sep 27;7(9):e46048. doi: 10.1371/journal.pone.0046048

Table 3. Clade-Scale Amino Acid Substitutions from the N, P, M, F and L Proteins of 40 Recently Sequenced HPIV-1 Complete Genomes (the HN protein is described in greater detail in Table 4 and is not included here).

Protein	Substitutions by clades			Multiple substitutions
from	Clade 1	Clade 2	Clade 3
N gene	None	None	N498S	None
P gene	N56S, P123S, P125L,	G110D, D185N, P231Q, S247P, K270R, T282A, V534A	N70D, I90V, I111V, P141S, S162F, P182S, T267I, S268G, S/P274L, S321G, S324P, V534A	F8S/L^a, L151P/S^a, G473S/T^a
M gene	None	None	None	None
F gene	E5K	N321S	T493K, V526I, R546K	F8L/I^a
L gene	M718I, L1605F	N199D, I210F, V2165I	Q4L, V93I, T728A, I1176V, V1506I, N1598H, K1747R, T2209I	None

These residues have more than two amino acid variations.