Table 1. Clinical details of patients with paradoxical reactions treated with corticosteroids.
Age | Gender | Lesion Location | Time to Paradoxical Reaction (Days) | Initial Size of Lesion | Features of Paradoxical Reaction | Features after Steroid Therapy |
62 | F | Achilles region, ulcer | 21 | 2×5 cm ulcer; induration 13×4 cm | Increased wound discharge and pain | Ulcer unchanged; discharge and pain resolved |
83 | F | Posterior heel, ulcer | 92 | 3×3 cm ulcer; induration 5×8 cm | 8×4 cm induration and wound ooze | 2×2 cm lesion; no induration |
9 | F | Lower leg, ulcer | 53 | 1 cm ulcer; minimal induration | Marked induration and wound discharge | Ulcer unchanged; swelling and discharge resolved |
14 | F | Knee, ulcer | 17 | 8 mm ulcer; induration 2×2 cm | Induration 6×6 cm and wound discharge | Ulcer unchanged; induration and discharge resolved |
84 | M | Elbow, edematous lesion | 30 | No ulcer; induration 13×11 cm | Induration 28×20 cm | Induration resolved |
Time to paradoxical reaction was defined as the number of days from the commencement of antibiotics until the onset of the paradoxical reaction.