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. 2012 Sep 27;6(9):e1767. doi: 10.1371/journal.pntd.0001767

Table 1. Clinical details of patients with paradoxical reactions treated with corticosteroids.

Age Gender Lesion Location Time to Paradoxical Reaction (Days) Initial Size of Lesion Features of Paradoxical Reaction Features after Steroid Therapy
62 F Achilles region, ulcer 21 2×5 cm ulcer; induration 13×4 cm Increased wound discharge and pain Ulcer unchanged; discharge and pain resolved
83 F Posterior heel, ulcer 92 3×3 cm ulcer; induration 5×8 cm 8×4 cm induration and wound ooze 2×2 cm lesion; no induration
9 F Lower leg, ulcer 53 1 cm ulcer; minimal induration Marked induration and wound discharge Ulcer unchanged; swelling and discharge resolved
14 F Knee, ulcer 17 8 mm ulcer; induration 2×2 cm Induration 6×6 cm and wound discharge Ulcer unchanged; induration and discharge resolved
84 M Elbow, edematous lesion 30 No ulcer; induration 13×11 cm Induration 28×20 cm Induration resolved

Time to paradoxical reaction was defined as the number of days from the commencement of antibiotics until the onset of the paradoxical reaction.