Table 2. Sub- and supra-threshold responses in Control and with presence of GABAA receptors blocker (DNDS).
Control | GABAA blocker DNDS | ||||||||
Oscill. behavior | Immediately after break-in | >20 minutes after break in | p- value | n | Immediately after break-in | >20 minutes after break in | p- value | n | |
Short latency EPSP (%) | LTO | 34.3±10 | 32.6±11.8 | 0.80 | 6 | 49.1±27.1 | 36.1±14.6 | 0.19 | 7 |
SSTO | 16.7±2 | 43.0±1.9 | 0.49 | 3 | 86.1±13.2 | 56.4±19 | 0.14 | 4 | |
Long latency IPSP (%) | LTO | 93.6±7.9 | 87.5±3.8 | 0.11 | 6 | 85.3±11.4 | 25.4±10.6 | <0.01 | 7 |
SSTO | 83.8±3.9 | 81.9±11.2 | 0.88 | 3 | 93.5±4.7 | 39.9±14.4 | <0.01 | 4 | |
IPSP duration (ms) | LTO | 512±187 | 518±161 | 0.90 | 6 | 390±26 | 295±14 | 0.02 | 7 |
SSTO | 334±179 | 376±138 | 0.38 | 3 | 219±19 | 198±26 | 0.42 | 4 | |
IPSP peak amplitude (mV) | LTO | −7.6±2.0 | −6.0±1.9 | 0.18 | 6 | −6.5±1.5 | −3.4±1.0 | <0.01 | 7 |
SSTO | −8.2±2.7 | −6.7±1.3 | 0.37 | 3 | −10.96±3.9 | −4.2±1.8 | <0.01 | 4 | |
IPSP surface area (ms*mV) | LTO | 2738±1806 | 2261±1268 | 0.57 | 6 | 1737±599 | 654±150 | <0.01 | 7 |
SSTO | 1871±474 | 1896±458 | 0.27 | 3 | 1718±882 | 484±245 | 0.04 | 4 | |
Rebound (%) | LTO | 60.1±32 | 57.4±28.3 | 0.21 | 6 | 68.2±21.2 | 69±17.3 | 0.46 | 7 |
SSTO | 87±9.7 | 84.2±5.7 | 0.25 | 3 | 96.5±1.4 | 74.2±10.5 | <0.05 | 4 | |
Rebound amplitude (mV) | LTO | 9.52±4.2 | 10.9±4 | 0.30 | 6 | 6.9±2.3 | 8.1±2.9 | 0.09 | 7 |
SSTO | 13.9±3.7 | 13.5±4.2 | 0.81 | 3 | 10.2±2.1 | 11.85±2.3 | 0.3 | 4 |