Table 2.
Pre-ECMO clinical status and support §).
| Arterial blood gases | (n = 10) |
| PaO2 – mmHg | 50 (36-56) |
| PaCO2 – mmHg | 57 (31–142) |
| P/F ratio | 50 (36-56) |
| Mechanical ventilation | |
| PEEP – cmH2O | 15 (10–23) |
| FiO2 | 1 (1–1) |
| Respiratory rate – breaths/minute | 28 (18–90) |
| Tidal volume – mL | 275 (130–400) |
| Plateau pressure – cmH2O | 31 (25–46) |
| Pre-ECMO respiratory rescue maneuvers | |
| Alveolar recruitment – n (%) | 7 (70) |
| Neuromuscular blockade – n (%) | 6 (60) |
| Corticosteroids – n (%) | 4 (40) |
| High frequency ventilation – n (%) *) | 3 (30) |
| Tracheal gas insufflation – n (%) | 1 (10) |
| Hemodynamics | |
| Norepinephrine – n (%)/dosage (mcg/kg/minute) | 10 (100)/0.64 (0.28– 5.12) |
| Epinephrine – n (%)/dosage (mcg/kg/minute) | 2 (20)/0.44 (0.19–0.70) |
| Dobutamine – n (%)/dosage (mcg/kg/minute) | 3 (30)/15 (4-20) |
| Vasopressin – n (%)/dosage (mcg/minute) | 1 (10)/0.03 |
| Mean arterial blood pressure – mmHg | 63 (30–94) |
| Heart rate – beats/minute | 145 (109-180) |
| Metabolic | |
| Temperature - °C | 37.4 (36.6–41.2) |
| Lactate – mEq/L | 2.8 (1.6–4.1) |
| pH | 7.17 (6.9–7.41) |
| SBE – mEq/L # | -2.3 (-21.9–5.6) |
| Sedation, analgesia and neuromuscular blockers | |
| SAS | 1.5 (1.0–3.0) |
| Midazolam - n (%)/dosage (mg/kg/hour) | 4 (40)/0.16 (0.11–0.42) |
| Propofol - n (%)/dosage (mg/kg/hour) | 4 (40)/0.73 (0.21–1.69) |
| Fentanyl - n (%)/dosage (mcg/kg/hour) | 7 (70)/2.25 (0.85–6.28) |
| Thionembutal - n (%)/dosage (mg/kg/hour) | 1 (10)/3 |
| Atracurium - n (%)/dosage (mg) | 5 (50)/50 (50–50) |
| Cisatracurium - n (%)/dosage (mg) | 1 (10)/20 |
All quantitative data are presented as medians (minimum, maximum).
§
ECMO denotes extracorporeal membrane oxygenation.
*
High-frequency ventilation denotes high-frequency positive pressure ventilation (HFPPV).
# SBE denotes standard base excess.