Table 4.
Distal femoral microCT40 data from 4 month old congenic females. Data presented as mean ± SEM.
| Congenic strain | BV (mm2) | ‘p’ for BV | TV (mm2) | ‘p’ for TV | BV/TV (%) | ‘p’ for BV/TV | Trab.no (1/μm) | ‘p’ for No | Trab.thk (μm) | ‘p’ for Thk |
|---|---|---|---|---|---|---|---|---|---|---|
| B6 (64) | 0.157 ± 0.004 | 1.960 ± 0.013 | 8.0 ± 0.2 | 3.89 ± 0.02 | 47.1 ± 0.4 | |||||
| 4-2 (15) | 0.184 ± 0.008a | .0020 | 1.995 ± 0.028 | - - - | 8.8 ± 0.4 | - - - | 3.84 ± 0.05 | - - - | 87.7 ± 2.1a | .0001 |
| 4-5 (17) | 0.184 ± 0.007a | .0033 | 2.081 ± 0.029a | .0009 | 8.9 ± 0.3 | - - - | 3.85 ± 0.05 | - - - | 49.8 ± 0.8b | .0042 |
| 4-7 (25) | 0.191 ± 0.007a | .0001 | 2.038 ± 0.027b | .0090 | 9.3 ± 0.3a | .0006 | 4.04 ± 0.04a | .0033 | 48.0 ± 0.7 | - - - |
| 4-9 (20) | 0.176 ± 0.007 | - - - | 1.975 ± 0.025 | - - - | 9.0 ± 0.3b | .0053 | 4.00 ± 0.04b | .0128 | 48.3 ± 0.7 | - - - |
| 4-15(20) | 0.148 ± 0.006 | - - - | 1.976 ± 0.023 | - - - | 7.4 ± 0.3 | - - - | 3.77 ± 0.04b | .0138 | 48.8 ± 0.7 | - - - |
| 4-16 (20) | 0.152 ± 0.006 | - - - | 1.988 ± 0.024 | - - - | 7.6 ± 0.3 | - - - | 3.76 ± 0.04a | .0032 | 48.9 ± 0.7 | - - - |
| 4-13 (17) | 0.144 ± 0.007 | - - - | 1.973 ± 0.026 | - - - | 7.3 ± 0.3 | - - - | 3.79 ± 0.04 | - - - | 45.6 ± 0.7 | - - - |
| 4-22 (20) | 0.099 ± 0.007c | .0001 | 2.020 ± 0.028 | - - - | 4.7 ± 0.3c | .0001 | 3.48 ± 0.05c | .0001 | 43.9 ± 0.8c | .0011 |
| 4-19 (27) | 0.164 ± 0.008 | - - - | 2.145 ± 0.008a | .0001 | 7.6 ± 0.4 | - - - | 3.59 ± 0.04c | .0001 | 49.2 ± 0.8 | - - - |
| 4-21 (22) | 0.234 ± 0.008a | .0001 | 2.279 ± 0.026a | .0001 | 10.2 ± 0.3a | .0001 | 3.49 ± 0.04 c | .0001 | 53.8 ± 0.8a | .0001 |
| 4-17 (22) | 0.251 ± 0.007a | .0001 | 2.271 ± 0.031a | .0001 | 11.0 ± 0.3a | .0001 | 3.56 ± 0.04c | .0001 | 54.4 ± 0.7a | .0001 |
| 4-14 (20) | 0.175 ± 0.007 | - - - | 2.025 ± 0.023 | - - - | 8.6 ± 0.3 | - - - | 3.97 ± 0.05 | - - - | 47.6 ± 0.8 | - - - |
| 4-10 (20) | 0.206 ± 0.006a | .0001 | 2.046 ± 0.024b | .0044 | 10.2 ± 0.3a | .0001 | 4.23 ± 0.04a | .0001 | 48.0 ± 0.7 | - - - |
| 4-11 (23) | 0.241 ± 0.010a | .0001 | 1.923 ± 0.022 | - - - | 12.6 ± 0.5a | .0001 | 4.26 ± 0.04a | .0001 | 50.4 ± 0.8a | .0002 |
| 4-12 (19) | 0.143 ± 0.007 | - - - | 2.009 ± 0.024 | - - - | 7.1 ± 0.3 | - - - | 3.86 ± 0.04 | - - - | 44.0 ± 0.7c | .0005 |
| 4-6 (19) | 0.186 ± 0.007a | .0004 | 2.158 ± 0.025a | .0001 | 8.5 ± 0.3 | - - - | 3.87 ± 0.04 | - - - | 48.1 ± 0.7 | - - - |
| 4-4 (21) | 0.175 ± 0.007 | - - - | 1.994 ± 0.026 | - - - | 8.7 ± 0.3 | - - - | 3.96 ± 0.04 | - - - | 76.5 ± 2.2a | .0001 |
| 4-8 (20) | 0.179 ± 0.009 | - - - | 2.152 ± 0.040a | .0001 | 8.3 ± 0.4 | - - - | 3.85 ±0.05 | - - - | 47.5 ± 0.9 | - - - |
a
= significantly (p < 0.003) or
b
= suggestively (p < 0.01) increased from B6 controls;
c
= significantly (p < 0.003) or
d
= suggestively (p < 0.01) decreased from B6 controls