Table 1.
Demographic, Psychiatric, and Medical Characteristics of the Study Participants (n = 244)
| Variable | HIV− (n = 82) | HIV+ | p | |
|---|---|---|---|---|
| HAND− (n = 109) | HAND+ (n = 53) | |||
| Demographics | ||||
| Age (years) | 45.5 (13.2) | 45.7 (10.0) | 45.4 (10.9) | .823 |
| Education (years) | 13.2 (1.9) | 12.8 (2.0) | 12.9 (2.8) | .413 |
| Sex (% female) | 25.6 | 13.8 | 17.0 | .107 |
| Ethnicity (% Caucasian) | 52.4 | 56.9 | 56.6 | .811 |
| Psychiatric | ||||
| Current major depressive disorder (%) | 3.7 | 13.0 | 11.5 | .086 |
| Major depressive disorder (%) a | 30.9 | 51.9 | 57.7 | .003 |
| Generalized anxiety disorder (%)a | 3.7 | 9.3 | 11.5 | .203 |
| Substance dependence (%) a | 51.2 | 56.0 | 54.7 | .805 |
| POMS totalb | 38 (23, 60) | 46 (23, 67) | 53 (34, 84) | .025 |
| Medical | ||||
| Hepatitis C (%) | 11.0 | 15.2 | 26.9 | .048 |
| HIV Disease | ||||
| HIV duration (years) | – | 13.3 (7.9) | 12.6 (7.5) | .640 |
| AIDS (%) | – | 54.1 | 50.9 | .703 |
| HAART (%) | – | 88.1 | 88.5 | .915 |
| Nadir CD4b (cells/μl) | – | 200 (52, 312) | 200 (67, 363) | .569 |
| Current CD4b (cells/μl) | – | 501 (330, 725) | 527 (372, 802) | .269 |
| plasma HIV RNA log10 (% detectable) | – | 29.3 | 23.1 | .413 |
Note. WTAR = Wechsler Test of Adult Reading. POMS = Profile of Mood States. HAART = highly-active antiretroviral therapy. HAND = HIV-associated neurocognitive disorder.
a
Denotes any lifetime diagnosis.
b
Median (interquartile range)