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Tip30 deletion resulted in tumor development in mice. (a) Graph shows incidence of lung tumors arising in Tip30+/+, Tip30+/−, and Tip30−/− mice. (b) Representative image of lung adenocarcinoma arising in Tip30−/− mice. The arrow indicates a tumor mass. (c–e) Representative H&E- stained sections of pulmonary hyperplasia (c), pulmonary adenoma (d), pulmonary adenocarcinoma (e) arising in Tip30−/− mice. Scale bar, 20 µm.
